s11379 Validated

• Gene Symbol: PSMC4
• Gene Name: proteasome 26S subunit, ATPase 4
• Gene Aliases: MIP224, RPT3, S6, TBP-7, TBP7
• Chromosome Location: Chr.19: 39971005 - 39981764 on Build GRCh38
• UniGene ID: Hs.211594
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSMC4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006503.3	NP_006494.1	11	1396
	NM_153001.2	NP_694546.1	11	1303
GenBank mRNA	AF020736.1	-	11	1238
	AF038965.1	-	11	1220
	AK290285.1	-	11	1204
	AK313183.1	-	11	1238
	BC000343.2	-	11	1218	2823007
	BC010396.1	-	11	1142	4046205
	BC014488.1	-	11	1218	4899042
	BC018811.2	-	11	1218
	BT007232.1	-	11	1198
	U27515.1	-	11	1210

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_057122, D50695, BC063145, FQ226113, FQ225557.
This siRNA also targets the following transcripts in Mouse: NM_011874, AK077507, AK167041, BC092265, AK167528, and others.

Matching Taqman Gene Expression Assay:

Hs00197826_m1

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
blastocyst development
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
proteolysis
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of proteasomal protein catabolic process

Function(s)

protein binding
ATP binding
ATPase activity
TBP-class protein binding
proteasome-activating ATPase activity