s11381 Validated

• Gene Symbol: PSMC5
• Gene Name: proteasome 26S subunit, ATPase 5
• Gene Aliases: S8, SUG-1, SUG1, TBP10, TRIP1, p45, p45/SUG
• Chromosome Location: Chr.17: 63827410 - 63832027 on Build GRCh38
• UniGene ID: Hs.79387
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSMC5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199163.1	NP_001186092.1	7	840
	NM_002805.5	NP_002796.4	7	705
GenBank mRNA	AF035309.1	-		783
	AK095836.1	-	6	1939
	AK098484.1	-		1869
	AK290758.1	-	7	803
	AK291878.1	-	7	677
	BC001932.1	-	7	656	2820259
	BC002367.2	-	7	635	2821416
	BC127888.1	-	5	547
	D44467.1	-	7	635
	L38810.1	-	7	642

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031149, AB000491, BC058462, FQ233831, FQ213263, and others.

Matching Taqman Gene Expression Assay:

Hs00267687_m1

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
transcription from RNA polymerase II promoter
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
negative regulation of programmed cell death
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of inclusion body assembly
positive regulation of canonical Wnt signaling pathway
positive regulation of proteasomal protein catabolic process

Function(s)

transcription cofactor activity
protein binding
ATP binding
transcription factor binding
ATPase activity
TBP-class protein binding
thyrotropin-releasing hormone receptor binding
proteasome-activating ATPase activity