s11456

• Gene Symbol: PTGER4
• Gene Name: prostaglandin E receptor 4
• Gene Aliases: EP4, EP4R
• Chromosome Location: Chr.5: 40679930 - 40740932 on Build GRCh38
• UniGene ID: Hs.199248
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PTGER4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000958.2	NP_000949.1	2	1406
	XM_017009656.1	XP_016865145.1	1	857
	XM_017009657.1	XP_016865146.1	1	857
	XM_017009658.1	XP_016865147.1	1	857
	XM_017009659.1	XP_016865148.1	1	857
GenBank mRNA	AY429109.1	-	1	814
	BC101534.1	-	2	873	8069040
	BC113523.1	-	2	873	8322575
	D28472.1	-	2	898
	L25124.1	-	2	1399
	L28175.1	-	2	1202

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_032076, XM_006231996, D28860, U94709.
This siRNA also targets the following transcripts in Mouse: NM_008965, NM_001136079, BC011193, D13458, AK156428, and others.

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

negative regulation of peptide secretion
immune response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
JNK cascade
female pregnancy
positive regulation of cell proliferation
response to mechanical stimulus
positive regulation of gene expression
negative regulation of hydrogen peroxide metabolic process
regulation of circadian sleep/wake cycle, wakefulness
positive regulation of smooth muscle cell migration
positive regulation of cAMP biosynthetic process
response to lipopolysaccharide
response to progesterone
positive regulation of interleukin-8 production
negative regulation of integrin activation
positive regulation of urine volume
positive regulation of renal sodium excretion
T-helper cell differentiation
negative regulation of circadian sleep/wake cycle, REM sleep
chemokinesis
response to drug
positive regulation of tyrosine phosphorylation of Stat3 protein
response to amino acid
positive regulation of osteoblast differentiation
positive regulation of bone resorption
positive regulation of cell adhesion
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of cytokine secretion
negative regulation of interleukin-1 alpha secretion
positive regulation of cytokine secretion
negative regulation of inflammatory response
positive regulation of inflammatory response
regulation of stress fiber assembly
negative regulation of nitric-oxide synthase biosynthetic process
maternal process involved in parturition
bone development
positive regulation of mucus secretion
ERK1 and ERK2 cascade
cellular response to mechanical stimulus
cellular response to glucose stimulus
cellular response to interleukin-1
cellular response to prostaglandin E stimulus
positive regulation of wound healing
ductus arteriosus closure
positive regulation of hyaluronan biosynthetic process
response to salt
negative regulation of ductus arteriosus closure
negative regulation of small intestine smooth muscle contraction
positive regulation of calcitonin secretion
positive regulation of chemokinesis
positive regulation of matrix metallopeptidase secretion
negative regulation of tumor necrosis factor secretion
negative regulation of endothelin secretion
positive regulation of substance P secretion, neurotransmission
response to water-immersion restraint stress
positive regulation of antral ovarian follicle growth
positive regulation of neutrophil extravasation
negative regulation of eosinophil extravasation
positive regulation of interleukin-10 secretion

Function(s)

prostaglandin E receptor activity
protein binding