s1150

• Gene Symbol: AES
• Gene Name: amino-terminal enhancer of split
• Gene Aliases: AES-1, AES-2, ESP1, GRG, GRG5, Grg-5, TLE5
• Chromosome Location: Chr.19: 3052910 - 3063107 on Build GRCh38
• UniGene ID: Hs.515053
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: AES
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130.5	NP_001121.2	4	394
	NM_198969.1	NP_945320.1	4	461
	NM_198970.1	NP_945321.1	4	394
	XM_006722664.1	XP_006722727.1	4	602
GenBank mRNA	AF072902.1	-	4	297
	AK094591.1	-	4	603
	AK095154.1	-	1	446
	AK314713.1	-	4	300
	BC113735.1	-	4	448	8322787
	BC113737.1	-	4	448	8322789
	BG913049.1	-	4	381
	BM550097.1	-		351
	BM908356.1	-		422
	U04241.1	-	4	261
	X73357.1	-	4	215
	X73358.1	-	3	185

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019220, BC101855, L14462.
This siRNA also targets the following transcripts in Mouse: NM_001276288, NM_010347, BC132217, BC132219, AK131994, and others.

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
multicellular organism development
organ morphogenesis
negative regulation of gene expression
Wnt signaling pathway
negative regulation of protein binding
negative regulation of transcription, DNA-templated
negative regulation of response to cytokine stimulus
response to interleukin-1
negative regulation of canonical Wnt signaling pathway
positive regulation of anoikis

Function(s)

transcription corepressor activity
protein binding