s11712 Validated

• Gene Symbol: RAC1
• Gene Name: ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
• Gene Aliases: MIG5, Rac-1, TC-25, p21-Rac1
• Chromosome Location: Chr.7: 6374495 - 6403967 on Build GRCh38
• UniGene ID: Hs.413812
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RAC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006908.4	NP_008839.2	6	959
	NM_018890.3	NP_061485.1	7	1016
GenBank mRNA	AK054993.1	-	6	934
	AK291815.1	-	7	963
	BC050687.1	-	6	906	6149377

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_134366, XM_008768986, AY491395.
This siRNA also targets the following transcripts in Mouse: NM_009007, AK009017, AK076023, AK211591, AK166383, and others.

Matching Taqman Gene Expression Assay:

Hs00251654_m1

Panther Classification:

Molecular Function -

small GTPase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
auditory receptor cell morphogenesis
mast cell chemotaxis
epithelial cell morphogenesis
movement of cell or subcellular component
inflammatory response
hyperosmotic response
cell adhesion
cell-matrix adhesion
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
axon guidance
blood coagulation
cell proliferation
regulation of cell size
response to wounding
anatomical structure morphogenesis
regulation of hydrogen peroxide metabolic process
positive regulation of lamellipodium assembly
regulation of fibroblast migration
positive regulation of cell-substrate adhesion
regulation of neuron maturation
cerebral cortex radially oriented cell migration
embryonic olfactory bulb interneuron precursor migration
cerebral cortex GABAergic interneuron development
lamellipodium assembly
actin cytoskeleton organization
actin filament polymerization
platelet activation
regulation of cell migration
positive regulation of actin filament polymerization
T cell costimulation
ruffle organization
negative regulation of interleukin-23 production
substrate adhesion-dependent cell spreading
positive regulation of Rho protein signal transduction
intracellular signal transduction
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
engulfment of apoptotic cell
cell-cell junction organization
bone resorption
positive regulation of DNA replication
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
negative regulation of receptor-mediated endocytosis
anatomical structure arrangement
dendrite morphogenesis
cell motility
homeostasis of number of cells within a tissue
regulation of defense response to virus by virus
regulation of small GTPase mediated signal transduction
positive regulation of stress fiber assembly
localization within membrane
positive regulation of focal adhesion assembly
synaptic transmission, GABAergic
Wnt signaling pathway, planar cell polarity pathway
regulation of respiratory burst
cellular response to mechanical stimulus
semaphorin-plexin signaling pathway
dopaminergic neuron differentiation
protein localization to plasma membrane
positive regulation of neutrophil chemotaxis
cochlea morphogenesis
ruffle assembly
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

GTPase activity
protein binding
GTP binding
Rab GTPase binding
enzyme binding
protein kinase binding
GTP-dependent protein binding
thioesterase binding
histone deacetylase binding
Rho GDP-dissociation inhibitor binding