s11749 Validated

• Gene Symbol: RAF1
• Gene Name: Raf-1 proto-oncogene, serine/threonine kinase
• Gene Aliases: CMD1NN, CRAF, NS5, Raf-1, c-Raf
• Chromosome Location: Chr.3: 12583601 - 12664201 on Build GRCh38
• UniGene ID: Hs.159130
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RAF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002880.3	NP_002871.1	10	1504
	XM_005265355.2	XP_005265412.1	10	1232
	XM_005265357.2	XP_005265414.1	9	1321
	XM_005265358.4	XP_005265415.1	9	1386
	XM_005265359.4	XP_005265416.1	8	1287
	XM_011533974.2	XP_011532276.1	11	1547
	XM_011533975.2	XP_011532277.1	10	1436
	XM_017006966.1	XP_016862455.1	9	1109
GenBank mRNA	AK226028.1	-	10	1420
	AK303561.1	-	9	1307
	AK303920.1	-	5	581
	AK312248.1	-	10	1398
	BC018119.2	-	10	1418	3904404
	KU178297.1	-	9	1089
	KU178298.1	-	10	1149
	KU178299.1	-	8	990
	X03484.1	-	10	1218

More Information

Matching Taqman Gene Expression Assay:

Hs00234119_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
response to hypoxia
stimulatory C-type lectin receptor signaling pathway
protein phosphorylation
apoptotic process
signal transduction
activation of adenylate cyclase activity
heart development
cell proliferation
negative regulation of cell proliferation
cell differentiation
platelet activation
thyroid gland development
negative regulation of protein complex assembly
positive regulation of peptidyl-serine phosphorylation
ion transmembrane transport
somatic stem cell population maintenance
regulation of Rho protein signal transduction
insulin secretion involved in cellular response to glucose stimulus
response to muscle stretch
wound healing
regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
intermediate filament cytoskeleton organization
regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
neurotrophin TRK receptor signaling pathway
thymus development
face development
death-inducing signaling complex assembly
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of cell motility

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
kinase activity
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
metal ion binding
protein heterodimerization activity