s11907

• Gene Symbol: REL
• Gene Name: REL proto-oncogene, NF-kB subunit
• Gene Aliases: C-Rel
• Chromosome Location: Chr.2: 60881495 - 60928171 on Build GRCh38
• UniGene ID: Hs.631886
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: REL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291746.1	NP_001278675.1	5, 6	873
	NM_002908.3	NP_002899.1	5, 6	873
	XM_011533010.2	XP_011531312.1	3, 4	360
	XM_017004627.1	XP_016860116.1	5, 6	794
GenBank mRNA	AK303926.1	-	5, 6	794
	BC117191.1	-	5, 6	712	40125742
	BC143885.1	-	5, 6	714	9052401
	X75042.1	-	5, 6	704

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009044, BC139770, AK031627, BC139447, BC139448.

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
inflammatory response
I-kappaB kinase/NF-kappaB signaling
negative regulation of gene expression
negative regulation of interferon-beta production
response to cytokine
NIK/NF-kappaB signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of transcription from RNA polymerase II promoter
negative regulation of neuron death

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding