s1192 Validated

• Gene Symbol: NR0B1
• Gene Name: nuclear receptor subfamily 0 group B member 1
• Gene Aliases: AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2
• Chromosome Location: Chr.X: 30304422 - 30309399 on Build GRCh38
• UniGene ID: Hs.268490
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NR0B1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000475.4	NP_000466.2	2	1304
GenBank mRNA	BC011564.1	-	2	1301	4637694
	HQ692832.1	-	2	1289
	S74720.1	-	2	1523

More Information

Matching Taqman Gene Expression Assay:

Hs00230864_m1

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
steroid biosynthetic process
spermatogenesis
protein localization
gonad development
male gonad development
hypothalamus development
pituitary gland development
male sex determination
adrenal gland development
intracellular receptor signaling pathway
negative regulation of intracellular steroid hormone receptor signaling pathway
Leydig cell differentiation
response to immobilization stress
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of cell differentiation
negative regulation of transcription, DNA-templated
Sertoli cell differentiation

Function(s)

DNA binding
steroid hormone receptor activity
transcription corepressor activity
RNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
protein domain specific binding
DNA hairpin binding
steroid hormone receptor binding
protein homodimerization activity
sequence-specific DNA binding