s12568

• Gene Symbol: CCL3
• Gene Name: C-C motif chemokine ligand 3
• Gene Aliases: G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3
• Chromosome Location: Chr.17: 36088256 - 36090160 on Build GRCh38
• UniGene ID: Hs.514107
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CCL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002983.2	NP_002974.1	1, 2	175
GenBank mRNA	BC071834.1	-	1, 2	147	5935287
	BC171831.1	-	1, 2	109	9054485
	BC171891.1	-	1, 2	109	9054545
	BX103455.1	-	1, 2	175
	D00044.1	-	1, 2	156
	D63785.1	-	1, 2	56
	M23452.1	-	1, 2	156
	M25315.1	-	1, 2	156
	X03754.1	-	1, 2	156

More Information

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
osteoblast differentiation
cell activation
monocyte chemotaxis
calcium ion transport
cellular calcium ion homeostasis
exocytosis
chemotaxis
inflammatory response
cytoskeleton organization
G-protein coupled receptor signaling pathway
cell-cell signaling
behavior
regulation of cell shape
response to toxic substance
positive regulation of gene expression
negative regulation of gene expression
T cell chemotaxis
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
calcium-mediated signaling
signaling
positive regulation of cell migration
negative regulation of bone mineralization
neutrophil chemotaxis
lipopolysaccharide-mediated signaling pathway
positive regulation of tumor necrosis factor production
eosinophil degranulation
protein kinase B signaling
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
astrocyte cell migration
negative regulation by host of viral transcription
negative regulation of osteoclast differentiation
eosinophil chemotaxis
macrophage chemotaxis
lymphocyte chemotaxis
positive regulation of interleukin-1 beta secretion
positive regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive chemotaxis
positive regulation of protein kinase B signaling
positive regulation of calcium ion transport
regulation of sensory perception of pain
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
response to cholesterol
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to organic cyclic compound
granulocyte chemotaxis
positive regulation of calcium ion import
positive regulation of natural killer cell chemotaxis

Function(s)

protein kinase activity
calcium-dependent protein kinase C activity
protein binding
chemokine activity
phospholipase activator activity
kinase activity
CCR1 chemokine receptor binding
CCR5 chemokine receptor binding
chemoattractant activity
identical protein binding