s128167

• Gene Symbol: Pde4b
• Gene Name: phosphodiesterase 4B, cAMP specific
• Gene Aliases: PDE4/IVb, Pde4B1, Pde4B2, Pde4B3, Pde4B4
• Chromosome Location: Chr.5: 121759236 - 122136814 on Build Rnor_6.0
• UniGene ID: Rn.37733
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pde4b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017031.2	NP_058727.2	5, 6	1100
GenBank mRNA	AF202732.1	-		958
	AF202733.1	-	5, 6	664
	J04563.1	-	2, 3	112
	U95748.1	-	5, 6	1100

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_019840, AF326555, AF326556.

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

neutrophil homeostasis
cAMP catabolic process
smooth muscle contraction
signal transduction
metabolic process
neutrophil chemotaxis
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
cellular response to drug
T cell receptor signaling pathway
leukocyte migration
cellular response to lipopolysaccharide
cellular response to epinephrine stimulus
regulation of cardiac muscle cell contraction
regulation of high voltage-gated calcium channel activity
negative regulation of relaxation of cardiac muscle

Function(s)

3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
cAMP binding
ion channel binding
metal ion binding