s128318

• Gene Symbol: Raf1
• Gene Name: v-raf-leukemia viral oncogene 1
• Gene Aliases: -
• Chromosome Location: Chr.4: 147532040 - 147592769 on Build Rnor_6.0
• UniGene ID: Rn.33262
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Raf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012639.2	NP_036771.1	2	448
	XM_008763217.1	XP_008761439.1	2	518
	XM_008763218.1	XP_008761440.1	2	698
GenBank mRNA	BC062071.1	-	2	448	5599540
	M15427.1	-		192

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_029780, AK036317, AB077145, BC015273, AK141745, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
response to hypoxia
cellular glucose homeostasis
positive regulation of protein phosphorylation
protein phosphorylation
heart development
negative regulation of cell proliferation
cell differentiation
negative regulation of protein complex assembly
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
intracellular signal transduction
insulin secretion involved in cellular response to glucose stimulus
response to muscle stretch
negative regulation of apoptotic process
intermediate filament cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
neurotrophin TRK receptor signaling pathway
death-inducing signaling complex assembly
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

protein serine/threonine kinase activity
MAP kinase kinase kinase activity
receptor signaling protein activity
protein binding
ATP binding
Ras GTPase binding
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
metal ion binding
protein heterodimerization activity