s128326

• Gene Symbol: Rb1
• Gene Name: retinoblastoma 1
• Gene Aliases: -
• Chromosome Location: Chr.15: 55081582 - 55209060 on Build Rnor_6.0
• UniGene ID: Rn.55115
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017045.1	NP_058741.1	25, 26	2872
GenBank mRNA	D25233.1	-	25, 26	2633
	L07126.1	-	4, 5	282

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000321, AK291258, M33647, AK300284, L41870, and others.

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
negative regulation of protein kinase activity
cell cycle arrest
Ras protein signal transduction
spermatogenesis
regulation of mitotic cell cycle
negative regulation of cell proliferation
chromatin modification
neuron differentiation
sister chromatid biorientation
neuron projection development
maintenance of mitotic sister chromatid cohesion
glial cell apoptotic process
skeletal muscle cell differentiation
neuron maturation
negative regulation of apoptotic process
enucleate erythrocyte differentiation
regulation of lipid kinase activity
myoblast differentiation
positive regulation of macrophage differentiation
negative regulation of cell cycle
positive regulation of mitotic metaphase/anaphase transition
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
negative regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
cell morphogenesis involved in neuron differentiation
negative regulation of epithelial cell proliferation
striated muscle cell differentiation
cell division
neuron apoptotic process
regulation of cell cycle
protein localization to chromosome, centromeric region
cellular response to xenobiotic stimulus
regulation of cohesin loading
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
hepatocyte apoptotic process
negative regulation of G1/S transition of mitotic cell cycle

Function(s)

core promoter binding
RNA polymerase II activating transcription factor binding
DNA binding
protein binding
transcription factor binding
enzyme binding
kinase binding
ubiquitin protein ligase binding
identical protein binding
phosphoprotein binding