s12875

• Gene Symbol: SIX1
• Gene Name: SIX homeobox 1
• Gene Aliases: BOS3, DFNA23, TIP39
• Chromosome Location: Chr.14: 60644698 - 60649489 on Build GRCh38
• UniGene ID: Hs.633506
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SIX1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005982.3	NP_005973.1	1, 2	816
GenBank mRNA	BC008874.2	-	1, 2	816	4138234
	BT007083.1	-	1, 2	568
	X91868.1	-	1, 2	843

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053759, AF323957.
This siRNA also targets the following transcripts in Mouse: NM_009189, AK131925, X80339, AK144753, BC023304, and others.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ureteric bud development
branching involved in ureteric bud morphogenesis
organ induction
kidney development
outflow tract morphogenesis
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
pattern specification process
skeletal muscle tissue development
sensory perception of sound
cell proliferation
regulation of synaptic growth at neuromuscular junction
regulation of skeletal muscle satellite cell proliferation
facial nerve morphogenesis
epithelial cell differentiation
thyroid gland development
olfactory placode formation
regulation of protein localization
protein localization to nucleus
aorta morphogenesis
inner ear morphogenesis
middle ear morphogenesis
negative regulation of neuron apoptotic process
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
thymus development
neuron fate specification
generation of neurons
embryonic cranial skeleton morphogenesis
embryonic skeletal system morphogenesis
inner ear development
regulation of epithelial cell proliferation
myoblast migration
pharyngeal system development
myotome development
fungiform papilla morphogenesis
trigeminal ganglion development
otic vesicle development
metanephric mesenchyme development
regulation of branch elongation involved in ureteric bud branching
positive regulation of ureteric bud formation
mesonephric tubule formation
ureter smooth muscle cell differentiation
positive regulation of secondary heart field cardioblast proliferation
cochlea morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
negative regulation of branching involved in ureteric bud morphogenesis
positive regulation of mesenchymal cell proliferation involved in ureter development
regulation of skeletal muscle cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding