s129418

• Gene Symbol: Chrna7
• Gene Name: cholinergic receptor, nicotinic, alpha 7 (neuronal)
• Gene Aliases: BTX, NARAD, nAChRa7
• Chromosome Location: Chr.1: 123898305 - 124039253 on Build Rnor_6.0
• UniGene ID: Rn.9698
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Chrna7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012832.3	NP_036964.3	6	489
	XM_008759497.1	XP_008757719.1	4	4347
	XM_008759498.1	XP_008757720.1	7	636
GenBank mRNA	AY574256.1	-	6	489
	AY671974.1	-	7	579
	L31619.1	-	6	511
	S53987.1	-		530

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_007390, L37663, AF325348, AK157809, AF225980, and others.

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

activation of MAPK activity
response to hypoxia
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
ion transport
calcium ion transport
cellular calcium ion homeostasis
endocytosis
signal transduction
synaptic transmission, cholinergic
memory
positive regulation of cell proliferation
associative learning
regulation of norepinephrine secretion
neuronal action potential
sperm motility
response to food
regulation of synaptic transmission, dopaminergic
negative regulation of interleukin-1 beta production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
ion transmembrane transport
response to nicotine
behavioral response to nicotine
T cell activation
B cell activation
regulation of membrane potential
dopamine biosynthetic process
ovulation cycle
response to ethanol
positive regulation of angiogenesis
behavioral response to ethanol
regulation of inflammatory response
negative regulation of inflammatory response
cognition
generation of ovulation cycle rhythm
cation transmembrane transport

Function(s)

beta-amyloid binding
acetylcholine-activated cation-selective channel activity
protein binding
drug binding
adenylate cyclase binding
acetylcholine receptor activity
toxic substance binding
chloride channel regulator activity
protein kinase binding
acetylcholine-gated cation channel activity
acetylcholine binding
protein homodimerization activity
ATPase binding
scaffold protein binding