s13542 Validated

• Gene Symbol: STAT6
• Gene Name: signal transducer and activator of transcription 6
• Gene Aliases: D12S1644, IL-4-STAT, STAT6B, STAT6C
• Chromosome Location: Chr.12: 57095404 - 57111433 on Build GRCh38
• UniGene ID: Hs.524518
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: STAT6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001178078.1	NP_001171549.1	16	2118
	NM_001178079.1	NP_001171550.1	16	2044
	NM_001178080.1	NP_001171551.1	15	1962
	NM_001178081.1	NP_001171552.1	14	1823
	NM_003153.4	NP_003144.3	16	2099
	NR_033659.1		15	1960
	XM_006719575.2	XP_006719638.1	17	2096
	XM_011538703.2	XP_011537005.1	17	2173
	XM_011538704.2	XP_011537006.1	18	2184
	XM_011538705.2	XP_011537007.1	18	2294
	XM_011538706.2	XP_011537008.1	18	2150
	XM_011538707.2	XP_011537009.1	17	2135
	XM_011538708.2	XP_011537010.1	16	1977
	XM_011538709.2	XP_011537011.1	17	2011
GenBank mRNA	AB103089.1	-	10	1271
	AK290431.1	-	16	2047
	AK291044.1	-	16	2045
	AK298721.1	-	14	1643
	AK299094.1	-	15	1896
	AK308751.1	-	16	1939
	AK312471.1	-	16	1965
	AK316142.1	-	15	1906
	AK316236.1	-	15	1737
	AY615283.1	-	4	348
	BC075852.1	-	16	1900	5530399
	BT007380.1	-	15	1793
	U16031.1	-	16	1958

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009284, AK149563, AK163053, AF481808, AF481809, and others.

Matching Taqman Gene Expression Assay:

Hs00598618_m1

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
T-helper 1 cell lineage commitment
negative regulation of type 2 immune response
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
signal transduction
positive regulation of type I interferon production
mammary gland epithelial cell proliferation
interleukin-4-mediated signaling pathway
regulation of cell proliferation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of isotype switching to IgE isotypes
mammary gland morphogenesis
cellular response to hydrogen peroxide
cellular response to reactive nitrogen species

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
protein binding
protein phosphatase binding
identical protein binding