s136458

• Gene Symbol: Ctnnb1
• Gene Name: catenin (cadherin associated protein), beta 1
• Gene Aliases: Catnb
• Chromosome Location: Chr.8: 129617770 - 129628378 on Build Rnor_6.0
• UniGene ID: Rn.112601
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ctnnb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053357.2	NP_445809.2	8	1295
	XM_008766691.1	XP_008764913.1	8	1378
GenBank mRNA	AF121265.1	-	8	1295
	FQ222424.1	-		1488
	FQ224468.1	-		1493

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_007614, NM_001165902, BC043481, BC043078, M90364, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
embryonic axis specification
cell morphogenesis involved in differentiation
skeletal system development
patterning of blood vessels
vasculogenesis
branching involved in ureteric bud morphogenesis
in utero embryonic development
gastrulation with mouth forming second
endoderm formation
cell fate specification
cell fate determination
endodermal cell fate commitment
neuron migration
kidney development
neural plate development
liver development
vasculature development
positive regulation of neuroblast proliferation
positive regulation of mesenchymal cell proliferation
lens morphogenesis in camera-type eye
regulation of secondary heart field cardioblast proliferation
mesenchymal to epithelial transition involved in metanephros morphogenesis
metanephros morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell adhesion
cell-matrix adhesion
chemical synaptic transmission
ectoderm development
glial cell fate determination
midgut development
heart development
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
response to hormone
anterior/posterior axis specification
dorsal/ventral axis specification
dorsal/ventral pattern formation
proximal/distal pattern formation
cellular process
regulation of gene expression
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
positive regulation of heparan sulfate proteoglycan biosynthetic process
Schwann cell proliferation
response to organic cyclic compound
Wnt signaling pathway
morphogenesis of embryonic epithelium
single organismal cell-cell adhesion
layer formation in cerebral cortex
central nervous system vasculogenesis
hair cycle process
hemopoiesis
cell differentiation
T cell differentiation
osteoclast differentiation
lung development
male genitalia development
regulation of epithelial cell differentiation
positive regulation of epithelial cell differentiation
forebrain development
regulation of centriole-centriole cohesion
pancreas development
hair follicle morphogenesis
regulation of myelination
positive regulation of telomere maintenance via telomerase
negative regulation of chondrocyte differentiation
response to estradiol
T cell differentiation in thymus
negative regulation of protein sumoylation
response to cytokine
adherens junction organization
adherens junction assembly
protein localization to cell surface
cellular protein localization
embryonic heart tube development
genitalia morphogenesis
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
embryonic skeletal limb joint morphogenesis
regulation of cell proliferation
regulation of T cell proliferation
odontogenesis of dentin-containing tooth
response to drug
regulation of cell fate specification
embryonic digit morphogenesis
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
skin development
response to estrogen
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
canonical Wnt signaling pathway involved in negative regulation of apoptotic process
myoblast differentiation
bone resorption
regulation of cell differentiation
negative regulation of cell differentiation
positive regulation of endothelial cell differentiation
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
regulation of osteoclast differentiation
negative regulation of osteoclast differentiation
positive regulation of fibroblast growth factor receptor signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of mitotic cell cycle, embryonic
response to cadmium ion
chromatin-mediated maintenance of transcription
cell maturation
synaptic vesicle transport
animal organ development
thymus development
oocyte development
embryonic foregut morphogenesis
regulation of smooth muscle cell proliferation
negative regulation of oligodendrocyte differentiation
synapse organization
smooth muscle cell differentiation
protein heterooligomerization
positive regulation of telomerase activity
oviduct development
canonical Wnt signaling pathway
limb development
trachea morphogenesis
trachea formation
epithelial tube branching involved in lung morphogenesis
lung cell differentiation
lung-associated mesenchyme development
lung induction
epithelial cell differentiation involved in prostate gland development
positive regulation of epithelial cell proliferation involved in prostate gland development
hair follicle placode formation
mesenchymal cell proliferation involved in lung development
positive regulation of branching involved in lung morphogenesis
endothelial tube morphogenesis
fungiform papilla formation
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
sympathetic ganglion development
regulation of centromeric sister chromatid cohesion
cellular response to mechanical stimulus
cellular response to growth factor stimulus
cellular response to organic cyclic compound
cellular response to indole-3-methanol
renal system development
renal vesicle formation
renal inner medulla development
renal outer medulla development
nephron tubule formation
regulation of nephron tubule epithelial cell differentiation
regulation of calcium ion import
negative regulation of neuron death
cellular response to insulin-like growth factor stimulus
regulation of protein localization to cell surface
positive regulation of determination of dorsal identity
negative regulation of apoptotic signaling pathway

Function(s)

RNA polymerase II activating transcription factor binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
signal transducer activity
protein binding
protein C-terminus binding
transcription factor binding
enzyme binding
kinase binding
protein phosphatase binding
estrogen receptor binding
protein complex binding
ionotropic glutamate receptor binding
nuclear hormone receptor binding
transcription regulatory region DNA binding
ion channel binding
alpha-catenin binding
cadherin binding
SMAD binding
nitric-oxide synthase binding
I-SMAD binding
R-SMAD binding
repressing transcription factor binding
euchromatin binding