s136493

• Gene Symbol: Tcf4
• Gene Name: transcription factor 4
• Gene Aliases: -
• Chromosome Location: Chr.18: 65285320 - 65507983 on Build Rnor_6.0
• UniGene ID: Rn.23354
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tcf4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053369.1	NP_445821.1	14, 15	1509
GenBank mRNA	AF149284.1	-	14, 15	1509
	FQ221525.1	-		1272
	FQ226283.1	-	5, 6	648
	FQ227003.1	-	2, 3	266
	FQ232404.1	-	2, 3	265
	FQ233045.1	-	10, 11	1141
	U09228.1	-	8, 9	928

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001083967, NM_013685, U16321, AK081012, AK028748, and others.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein-DNA complex assembly

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, TFIIB-class binding
TFIIB-class transcription factor binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein C-terminus binding
bHLH transcription factor binding
protein heterodimerization activity
E-box binding