s136736

• Gene Symbol: Hdac3
• Gene Name: histone deacetylase 3
• Gene Aliases: -
• Chromosome Location: Chr.18: 31073057 - 31094347 on Build Rnor_6.0
• UniGene ID: Rn.17284
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053448.1	NP_445900.1	11, 12	1016
GenBank mRNA	AF321131.1	-	11, 12	1016
	BC061988.1	-	11, 12	1019	5599517

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010411, AK145158, AK206656, AK208847, BC139301, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
positive regulation of protein phosphorylation
transcription, DNA-templated
protein deacetylation
regulation of mitotic cell cycle
negative regulation of myotube differentiation
histone deacetylation
regulation of protein stability
response to nutrient levels
positive regulation of TOR signaling
negative regulation of interleukin-1 production
negative regulation of tumor necrosis factor production
circadian regulation of gene expression
regulation of multicellular organism growth
response to drug
positive regulation of transcription factor import into nucleus
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JNK cascade
negative regulation of protein export from nucleus
spindle assembly
histone H3-K9 modification
histone H3 deacetylation
histone H4 deacetylation
cellular response to mechanical stimulus
cellular response to parathyroid hormone stimulus
cellular response to fluid shear stress
response to dexamethasone
positive regulation of type B pancreatic cell apoptotic process
negative regulation of cardiac muscle cell differentiation

Function(s)

DNA binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
enzyme binding
cyclin binding
chromatin DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
histone deacetylase binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
GTPase binding
NAD-dependent histone deacetylase activity (H3-K18 specific)