s13675

Gene Symbol:

XCL1 XCL2

Gene Name:

X-C motif chemokine ligand 1

X-C motif chemokine ligand 2

Gene Aliases:

ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1

SCM-1b, SCM1B, SCYC2

Chromosome Location:

Chr.1: 168574128 - 168582077 on Build GRCh38

Chromosome Location:

Chr.1: 168540765 - 168543997 on Build GRCh38

UniGene ID:

Hs.546295

Hs.458346

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: XCL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002995.2	NP_002986.1	2	311
	XM_011509865.2	XP_011508167.1	3	2536
GenBank mRNA	BC069817.1	-	2	164	7262708
	BC070309.1	-	2	179	30416260
	BF433809.1	-	2	311
	D43768.1	-	2	166
	U23772.1	-	2	160
	X86474.1	-	2	170

Gene Symbol: XCL2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003175.3	NP_003166.1	2	179
GenBank mRNA	BC069360.1	-	2	146	7262751
	BC070308.1	-	2	179	30413788
	CD521967.1	-	2	182

More Information

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
monocyte chemotaxis
positive regulation of leukocyte chemotaxis
negative regulation of T cell cytokine production
positive regulation of T cell cytokine production
negative regulation of T-helper 1 type immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
response to virus
positive regulation of T cell chemotaxis
neutrophil chemotaxis
negative regulation of interferon-gamma production
negative regulation of interleukin-2 production
positive regulation of interleukin-10 production
mature natural killer cell chemotaxis
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of GTPase activity
negative regulation of transcription, DNA-templated
regulation of inflammatory response
positive regulation of inflammatory response
release of sequestered calcium ion into cytosol
positive regulation of release of sequestered calcium ion into cytosol
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to interleukin-4
cellular response to tumor necrosis factor
cellular response to transforming growth factor beta stimulus
positive regulation of transforming growth factor beta production
positive regulation of granzyme B production
positive regulation of neutrophil chemotaxis
positive regulation of thymocyte migration
positive regulation of natural killer cell chemotaxis
positive regulation of granzyme A production
negative regulation of T-helper 1 cell activation
positive regulation of B cell chemotaxis
positive regulation of T-helper 2 cell cytokine production
positive regulation of T-helper 1 cell cytokine production
positive regulation of immunoglobulin production in mucosal tissue
negative regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD8-positive, alpha-beta T cell proliferation
inflammatory response
blood circulation
lymphocyte chemotaxis

Function(s)

chemokine activity
chemokine receptor binding
protein homodimerization activity
CCR chemokine receptor binding
protein binding