s137623

• Gene Symbol: Braf
• Gene Name: B-Raf proto-oncogene, serine/threonine kinase
• Gene Aliases: -
• Chromosome Location: Chr.4: 67389331 - 67520487 on Build Rnor_6.0
• UniGene ID: Rn.205813
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Braf
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_006236357.2	XP_006236419.2	6	760
	XM_006236358.2	XP_006236420.2	6	760
	XM_006236359.2	XP_006236421.2	6	760
	XM_231692.8	XP_231692.4	7	766

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_004333, M95712, BC101757, BC112079, AK314346.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
myeloid progenitor cell differentiation
protein phosphorylation
visual learning
positive regulation of gene expression
negative regulation of fibroblast migration
cell differentiation
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
cellular response to drug
regulation of cell proliferation
negative regulation of apoptotic process
CD4-positive, alpha-beta T cell differentiation
positive T cell selection
response to peptide hormone
negative regulation of neuron apoptotic process
alpha-beta T cell differentiation
regulation of axon regeneration
positive regulation of axon regeneration
positive regulation of axonogenesis
protein heterooligomerization
positive regulation of stress fiber assembly
response to cAMP
long-term synaptic potentiation
head morphogenesis
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of synaptic vesicle exocytosis
negative regulation of endothelial cell apoptotic process

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity