s138230

Gene Symbol:

Map3k1 LOC100912399

Gene Name:

mitogen activated protein kinase kinase kinase 1

mitogen-activated protein kinase kinase kinase 1-like

Gene Aliases:

Mekk1

-

Chromosome Location:

Chr.2: 43329516 - 43393203 on Build Rnor_6.0

Chromosome Location:

Chr.2: 43938558 - 44000007 on Build Rnor_6.0

UniGene ID:

Rn.11081

-

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Map3k1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053887.1	NP_446339.1	1, 2	975
GenBank mRNA	JQ013733.1	-	1, 2	492
	U48596.1	-	1, 2	975

Gene Symbol: LOC100912399
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_006231926.2	XP_006231988.2		956

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011945, AF117340, AB014614.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
protein polyubiquitination
epithelial cell morphogenesis
protein phosphorylation
response to osmotic stress
transforming growth factor beta receptor signaling pathway
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
apoptotic mitochondrial changes
peptidyl-serine phosphorylation
regulation of cell migration
positive regulation of actin filament polymerization
negative regulation of actin filament bundle assembly
wound healing
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
camera-type eye development
positive regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of JUN kinase activity
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
positive regulation of viral transcription
protein oligomerization
eyelid development in camera-type eye
cellular response to mechanical stimulus

Function(s)

protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
MAP kinase kinase kinase activity
ubiquitin-protein transferase activity
protein binding
ATP binding
zinc ion binding
JUN kinase binding
JUN kinase kinase activity
protein kinase binding
mitogen-activated protein kinase kinase binding
sphingolipid binding
mitogen-activated protein kinase binding