s139178

• Gene Symbol: Hey2
• Gene Name: hes-related family bHLH transcription factor with YRPW motif 2
• Gene Aliases: Herp1
• Chromosome Location: Chr.1: 29191170 - 29201257 on Build Rnor_6.0
• UniGene ID: Rn.58672
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hey2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_130417.1	NP_569101.1	4	354

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_012259, BT020067, AK303890, BT020068, AF237949, and others.
This siRNA also targets the following transcripts in Mouse: NM_013904, BC103575, AK158000, AF232240, AK031506, and others.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
vasculogenesis
muscular septum morphogenesis
outflow tract morphogenesis
atrioventricular valve development
pulmonary valve morphogenesis
tricuspid valve morphogenesis
tricuspid valve formation
endocardial cushion to mesenchymal transition involved in heart valve formation
cardiac ventricle morphogenesis
cardiac left ventricle morphogenesis
cardiac right ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
cardiac muscle hypertrophy
transcription from RNA polymerase II promoter
Notch signaling pathway
pattern specification process
heart development
anterior/posterior axis specification
positive regulation of heart rate
regulation of gene expression
negative regulation of gene expression
negative regulation of cardiac muscle cell apoptotic process
mesenchymal cell development
cardiac muscle hypertrophy in response to stress
ascending aorta morphogenesis
dorsal aorta morphogenesis
umbilical cord morphogenesis
cell fate commitment
regulation of auditory receptor cell differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
ventricular cardiac muscle cell development
positive regulation of cardiac muscle cell proliferation
cardiac epithelial to mesenchymal transition
heart trabecula formation
cardiac septum morphogenesis
ventricular septum morphogenesis
atrial septum morphogenesis
negative regulation of transcription initiation from RNA polymerase II promoter
labyrinthine layer blood vessel development
artery development
arterial endothelial cell differentiation
cardiac vascular smooth muscle cell development
coronary vasculature morphogenesis
pulmonary artery morphogenesis
protein-DNA complex assembly
cochlea development
vascular smooth muscle cell development
negative regulation of transcription regulatory region DNA binding
negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
regulation of vasculogenesis

Function(s)

transcription factor activity, RNA polymerase II core promoter sequence-specific
RNA polymerase II activating transcription factor binding
molecular_function
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
microsatellite binding
histone deacetylase binding
sequence-specific DNA binding
protein dimerization activity