s13950 Validated

• Gene Symbol: TDG
• Gene Name: thymine DNA glycosylase
• Gene Aliases: hTDG
• Chromosome Location: Chr.12: 103965815 - 103988878 on Build GRCh38
• UniGene ID: Hs.584809
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TDG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003211.4	NP_003202.3	3	558
	XM_005269125.1	XP_005269182.1	3	418
	XM_011538714.1	XP_011537016.1	2	388
	XM_011538715.1	XP_011537017.1	2	388
GenBank mRNA	AK295387.1	-	1	45
	AK299832.1	-	3	470
	AK303631.1	-	2	385
	AK309792.1	-	4	602
	AK311673.1	-	2	388
	AK313234.1	-	3	501
	AL710869.1	-	4	710
	BC019925.1	-	3	512
	BC037557.1	-	3	511	5184772
	DB162106.1	-	3	559

More Information

Matching Taqman Gene Expression Assay:

Hs00702322_s1

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
base-excision repair
base-excision repair, AP site formation
mismatch repair
transcription, DNA-templated
embryo development
covalent chromatin modification
protein sumoylation
negative regulation of protein binding
oxidative DNA demethylation
negative regulation of chromatin binding
regulation of gene expression, epigenetic
depyrimidination
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
damaged DNA binding
double-stranded DNA binding
uracil DNA N-glycosylase activity
protein kinase C binding
protein binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
DNA N-glycosylase activity
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding