s139768

• Gene Symbol: Pde5a
• Gene Name: phosphodiesterase 5A, cGMP-specific
• Gene Aliases: PDE5A2
• Chromosome Location: Chr.2: 226899409 - 227044916 on Build Rnor_6.0
• UniGene ID: Rn.10861
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pde5a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_133584.1	NP_598268.1	18, 19	2672
	XM_006233260.2	XP_006233322.1	18, 19	2600
GenBank mRNA	D89093.1	-	18, 19	2672

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_033430, NM_033437, NM_001083, AY264918, BC126233, and others.
This siRNA also targets the following transcripts in Mouse: NM_153422, AF541937, BC120486, BC119137.

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

response to hypoxia
regulation of the force of heart contraction
positive regulation of chronic inflammatory response
signal transduction
nervous system development
short-term memory
positive regulation of cardiac muscle hypertrophy
regulation of cGMP metabolic process
response to lipopolysaccharide
response to testosterone
negative regulation of T cell proliferation
vasodilation
positive regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of vasoconstriction
cGMP metabolic process
cGMP catabolic process
negative regulation of cardiac muscle contraction
relaxation of cardiac muscle
positive regulation of oocyte development

Function(s)

cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity