s14013

• Gene Symbol: TFAP4
• Gene Name: transcription factor AP-4 (activating enhancer binding protein 4)
• Gene Aliases: AP-4, bHLHc41
• Chromosome Location: Chr.16: 4257186 - 4273000 on Build GRCh38
• UniGene ID: Hs.513305
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TFAP4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003223.2	NP_003214.1	6	1059
	XM_011522633.2	XP_011520935.1	6	1195
	XM_011522635.2	XP_011520937.1	6	875
GenBank mRNA	AB209146.1	-	4	5410
	BC010576.1	-	6	948	4181538
	CR541726.1	-	6	805
	S73885.1	-	6	1063
	X57435.1	-	6	754

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108267, XM_006245820, XM_006245818, XM_006245823, XM_006245819, and others.
This siRNA also targets the following transcripts in Mouse: NM_031182, BC047270, AK166424, AF161262, BC054777, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
negative regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation by host of viral transcription
positive regulation by host of viral transcription
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cell cycle arrest
cellular response to dexamethasone stimulus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
E-box binding