s140868

• Gene Symbol: Ripk3
• Gene Name: receptor-interacting serine-threonine kinase 3
• Gene Aliases: Hcyp2, Rip3
• Chromosome Location: Chr.15: 34470793 - 34479741 on Build Rnor_6.0
• UniGene ID: Rn.7110
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ripk3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_139342.1	NP_647558.1	11	1744
GenBank mRNA	AF036537.2	-	11	1744

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of T cell mediated cytotoxicity
regulation of adaptive immune response
protein phosphorylation
I-kappaB kinase/NF-kappaB signaling
positive regulation of phosphatase activity
signal transduction by protein phosphorylation
activation of protein kinase activity
regulation of interferon-gamma production
T cell differentiation in thymus
NIK/NF-kappaB signaling
T cell homeostasis
regulation of activated T cell proliferation
protein autophosphorylation
lymph node development
spleen development
thymus development
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of transferase activity
positive regulation of ligase activity
positive regulation of oxidoreductase activity
positive regulation of necroptotic process
regulation of activation-induced cell death of T cells
necroptotic process
positive regulation of protein deacetylation
amyloid fibril formation
regulation of reactive oxygen species metabolic process
positive regulation of reactive oxygen species metabolic process
regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein kinase activity
protein serine/threonine kinase activity
NF-kappaB-inducing kinase activity
ATP binding
protein complex binding
identical protein binding