s1435 Validated

• Gene Symbol: APC
• Gene Name: APC, WNT signaling pathway regulator
• Gene Aliases: BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
• Chromosome Location: Chr.5: 112707505 - 112846239 on Build GRCh38
• UniGene ID: Hs.158932
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: APC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000038.5	NP_000029.2	16	5650
	NM_001127510.2	NP_001120982.1	17	5758
	NM_001127511.2	NP_001120983.2	14	5724
GenBank mRNA	AB210001.1	-	17	5722
	M73548.1	-	15	5606
	M74088.1	-	15	5583

More Information

Matching Taqman Gene Expression Assay:

Hs00181051_m1

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
cell fate specification
protein complex assembly
cellular component disassembly involved in execution phase of apoptosis
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
cell cycle arrest
mitotic spindle assembly checkpoint
cell adhesion
establishment or maintenance of cell polarity
pattern specification process
negative regulation of cell proliferation
Wnt signaling pathway
cell migration
positive regulation of cell migration
pancreas development
neuron projection development
positive regulation of pseudopodium assembly
regulation of microtubule-based process
response to drug
positive regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of cell differentiation
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of attachment of spindle microtubules to kinetochore
canonical Wnt signaling pathway
bicellular tight junction assembly
negative regulation of canonical Wnt signaling pathway
response to alcohol
beta-catenin destruction complex assembly
beta-catenin destruction complex disassembly
cellular response to nerve growth factor stimulus
regulation of glutamate metabolic process

Function(s)

protein binding
beta-catenin binding
microtubule binding
protein kinase regulator activity
protein kinase binding
protein complex binding
gamma-catenin binding
cadherin binding
microtubule plus-end binding