s1449 Validated

• Gene Symbol: BIRC2
• Gene Name: baculoviral IAP repeat containing 2
• Gene Aliases: API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1
• Chromosome Location: Chr.11: 102347182 - 102378670 on Build GRCh38
• UniGene ID: Hs.696238
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BIRC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001166.4	NP_001157.1	2	1498
	NM_001256163.1	NP_001243092.1	2	1775
GenBank mRNA	AK225856.1	-	1	490
	AK313446.1	-	1	303
	BC016174.1	-	1	74	3908352
	BC028578.1	-	2	1776	4831062
	BX647978.1	-	2	1445
	L49431.1	-	1	240
	U37547.1	-	1	1205
	U45879.1	-	1	283

More Information

Matching Taqman Gene Expression Assay:

Hs00236911_m1

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

protein polyubiquitination
response to hypoxia
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular component disassembly involved in execution phase of apoptosis
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
regulation of toll-like receptor signaling pathway
TRIF-dependent toll-like receptor signaling pathway
NIK/NF-kappaB signaling
regulation of RIG-I signaling pathway
regulation of cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of innate immune response
response to ethanol
regulation of cell differentiation
regulation of inflammatory response
protein heterooligomerization
response to cAMP
regulation of cell cycle
regulation of necroptotic process
necroptotic process
regulation of nucleotide-binding oligomerization domain containing signaling pathway
mitotic spindle assembly
negative regulation of ripoptosome assembly involved in necroptotic process
positive regulation of protein K63-linked ubiquitination
positive regulation of protein K48-linked ubiquitination
positive regulation of protein monoubiquitination
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity
regulation of reactive oxygen species metabolic process

Function(s)

transcription coactivator activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
transferase activity
ligase activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
protein N-terminus binding