s14570 Validated

• Gene Symbol: UBE2B
• Gene Name: ubiquitin conjugating enzyme E2 B
• Gene Aliases: E2-17kDa, HHR6B, HR6B, RAD6B, UBC2
• Chromosome Location: Chr.5: 134371176 - 134392108 on Build GRCh38
• UniGene ID: Hs.612096
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBE2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003337.3	NP_003328.1	4	649
GenBank mRNA	AK312012.1	-	4	313
	BC005979.1	-	4	256	4105643
	BC008404.1	-	4	316	4278820
	BC008470.1	-	4	316	4281004
	BT007071.1	-	4	229
	CR407634.1	-	4	229
	M74525.1	-	4	650
	X53251.1	-	4	267

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031138, XM_006246343, XM_008773893, BC070946, DN931313, and others.
This siRNA also targets the following transcripts in Mouse: NM_009458, AK152645, AK147785, AK010432, AK169229, and others.

Matching Taqman Gene Expression Assay:

Hs00163311_m1

Gene Ontology Categories:

Process(es)

protein polyubiquitination
in utero embryonic development
DNA repair
postreplication repair
maintenance of chromatin silencing
ubiquitin-dependent protein catabolic process
protein monoubiquitination
cellular response to DNA damage stimulus
spermatogenesis
sperm axoneme assembly
response to UV
positive regulation of reciprocal meiotic recombination
protein ubiquitination
negative regulation of histone phosphorylation
histone H2A ubiquitination
response to drug
DNA damage response, detection of DNA damage
negative regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of cAMP-mediated signaling
meiotic telomere clustering
protein stabilization
chiasma assembly
protein autoubiquitination
canonical Wnt signaling pathway
histone lysine demethylation
synaptonemal complex organization
protein K63-linked ubiquitination
protein K48-linked ubiquitination
protein K11-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
ubiquitin protein ligase activity
ubiquitin conjugating enzyme activity