s145758

• Gene Symbol: Nedd4l
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Gene Aliases: Nedd4-2
• Chromosome Location: Chr.18: 60392376 - 60719720 on Build Rnor_6.0
• UniGene ID: Rn.72824
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nedd4l
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008300.2	NP_001008301.2	14	1249
GenBank mRNA	GQ160815.1	-	13	1189
	GQ160816.1	-	13	1189

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_015277, NM_001144968, NM_001144969, NM_001144970, NM_001144967, and others.
This siRNA also targets the following transcripts in Mouse: NM_001114386, NM_031881, AK183000, AF277232, AK004969, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of systemic arterial blood pressure
regulation of membrane depolarization
protein monoubiquitination
response to salt stress
response to metal ion
positive regulation of sodium ion transport
negative regulation of sodium ion transport
protein ubiquitination
regulation of ion transmembrane transport
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
positive regulation of protein catabolic process
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
regulation of bicellular tight junction assembly
positive regulation of cation channel activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
potassium channel regulator activity
ligase activity
sodium channel regulator activity
potassium channel inhibitor activity
sodium channel inhibitor activity
ion channel binding
ubiquitin protein ligase activity