s14765 Validated

• Gene Symbol: VCP
• Gene Name: valosin containing protein
• Gene Aliases: ALS14, CMT2Y, HEL-220, HEL-S-70, IBMPFD, IBMPFD1, TERA, p97
• Chromosome Location: Chr.9: 35056068 - 35072742 on Build GRCh38
• UniGene ID: Hs.529782
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: VCP
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007126.3	NP_009057.1	3	649
GenBank mRNA	AF100752.1	-	3	472
	AK307735.1	-	3	464
	AK312310.1	-	3	531
	BC110913.1	-	3	459	6502535
	BC121794.1	-	3	456	40108360
	BC122550.1	-	3	456	40108357
	DA880782.1	-	3	649
	FJ224344.1	-	3	472
	FJ224352.1	-	3	472

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053864, U11760, BC060518.
This siRNA also targets the following transcripts in Mouse: NM_009503, AK214159, AK159509, AK028264, AK169140, and others.

Matching Taqman Gene Expression Assay:

Hs00997642_m1

Gene Ontology Categories:

Process(es)

DNA repair
double-strand break repair
NADH metabolic process
ER to Golgi vesicle-mediated transport
autophagy
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
positive regulation of mitochondrial membrane potential
protein ubiquitination
protein N-linked glycosylation via asparagine
viral genome replication
translesion synthesis
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
retrograde protein transport, ER to cytosol
positive regulation of protein complex assembly
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein hexamerization
ERAD pathway
regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
establishment of protein localization
positive regulation of protein catabolic process
ATP metabolic process
protein homooligomerization
aggresome assembly
error-free translesion synthesis
ER-associated misfolded protein catabolic process
flavin adenine dinucleotide catabolic process
autophagosome maturation
positive regulation of protein K63-linked deubiquitination
positive regulation of Lys63-specific deubiquitinase activity
regulation of aerobic respiration
positive regulation of oxidative phosphorylation
positive regulation of ubiquitin-specific protease activity
positive regulation of ATP biosynthetic process

Function(s)

protein binding
ATP binding
lipid binding
ATPase activity
protein phosphatase binding
protein domain specific binding
polyubiquitin binding
ubiquitin protein ligase binding
deubiquitinase activator activity
K48-linked polyubiquitin binding
MHC class I protein binding
identical protein binding
ADP binding
ubiquitin-like protein ligase binding
poly(A) RNA binding
BAT3 complex binding
ubiquitin-specific protease binding