s148152

• Gene Symbol: Pax2
• Gene Name: paired box 2
• Gene Aliases: -
• Chromosome Location: Chr.1: 264493579 - 264583883 on Build Rnor_6.0
• UniGene ID: Rn.137112
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pax2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001106361.1	NP_001099831.1	2, 3	234
	XM_006231443.2	XP_006231505.1	3, 4	952
	XM_008760403.1	XP_008758625.1	3, 4	949
	XM_008760404.1	XP_008758626.1	3, 4	952
	XM_008760405.1	XP_008758627.1	3, 4	949

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003989, NM_003987, NM_003990, NM_003988, NM_000278, and others.
This siRNA also targets the following transcripts in Mouse: NM_011037, BC148232, BC150484.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
urogenital system development
metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
cell fate determination
kidney development
mesonephros development
neural tube closure
optic cup morphogenesis involved in camera-type eye development
mesenchymal to epithelial transition involved in metanephros morphogenesis
retinal pigment epithelium development
transcription, DNA-templated
transcription from RNA polymerase II promoter
mesodermal cell fate specification
aging
positive regulation of cell proliferation
glial cell differentiation
optic nerve development
optic nerve morphogenesis
optic nerve structural organization
vestibulocochlear nerve formation
pancreas development
response to nutrient levels
regulation of metanephros size
ureter maturation
pronephric field specification
inner ear morphogenesis
regulation of apoptotic process
camera-type eye development
negative regulation of apoptotic process
regulation of programmed cell death
negative regulation of programmed cell death
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of cytolysis
positive regulation of transcription from RNA polymerase II promoter
animal organ development
pronephros development
brain morphogenesis
stem cell differentiation
positive regulation of epithelial cell proliferation
oxidation-reduction process
mesenchymal to epithelial transition
paramesonephric duct development
optic chiasma development
cellular response to hydrogen peroxide
cellular response to mechanical stimulus
cellular response to retinoic acid
cellular response to glucose stimulus
cellular response to epidermal growth factor stimulus
renal system development
metanephric mesenchyme development
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
metanephric mesenchymal cell differentiation
mesonephric tubule development
mesonephric tubule formation
mesonephric duct development
nephric duct formation
ureter development
ureter morphogenesis
metanephric collecting duct development
metanephric epithelium development
metanephric distal convoluted tubule development
metanephric nephron tubule formation
positive regulation of metanephric glomerulus development
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
regulation of metanephric nephron tubule epithelial cell differentiation
reactive oxygen species metabolic process
cochlea development
cochlea morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
negative regulation of mesenchymal cell apoptotic process involved in metanephros development
negative regulation of apoptotic process involved in metanephric collecting duct development
negative regulation of apoptotic process involved in metanephric nephron tubule development
negative regulation of reactive oxygen species metabolic process
positive regulation of metanephric DCT cell differentiation
positive regulation of optic nerve formation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter proximal region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
superoxide-generating NADPH oxidase activity
sequence-specific DNA binding
transcription regulatory region DNA binding
C2H2 zinc finger domain binding