s14973

• Gene Symbol: ZAP70
• Gene Name: zeta chain of T cell receptor associated protein kinase 70
• Gene Aliases: ADMIO2, IMD48, SRK, STCD, STD, TZK, ZAP-70
• Chromosome Location: Chr.2: 97712030 - 97744327 on Build GRCh38
• UniGene ID: Hs.234569
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ZAP70
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001079.3	NP_001070.2	11	1579
	NM_207519.1	NP_997402.1	3	597
	XM_017004867.1	XP_016860356.1	13	2980
	XM_017004868.1	XP_016860357.1	13	2962
	XM_017004869.1	XP_016860358.1	13	2980
	XM_017004870.1	XP_016860359.1	13	2980
GenBank mRNA	AB083211.1	-	3	597
	AL832287.1	-	4	2424
	BC039039.1	-	10	1233	5168073
	BC053878.1	-	11	1555	5757161
	L05148.1	-	11	1581

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012002, XM_006244761, XM_008766998, BC089855.

Gene Ontology Categories:

Process(es)

adaptive immune response
macrophage activation involved in immune response
neutrophil activation involved in immune response
protein phosphorylation
inflammatory response
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
peptidyl-tyrosine phosphorylation
T cell differentiation
positive regulation of cell adhesion mediated by integrin
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
T cell activation
B cell activation
positive regulation of mast cell degranulation
beta selection
positive thymic T cell selection
negative thymic T cell selection
innate immune response
positive regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of alpha-beta T cell differentiation
positive regulation of alpha-beta T cell proliferation
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway
B cell receptor signaling pathway
T cell aggregation
T cell migration
regulation of platelet aggregation

Function(s)

phosphotyrosine binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding