s158853

• Gene Symbol: Egln2
• Gene Name: egl-9 family hypoxia-inducible factor 2
• Gene Aliases: HIF-PH1, HPH-1, HPH-3, PHD-1, PHD1
• Chromosome Location: Chr.1: 83969456 - 83977662 on Build Rnor_6.0
• UniGene ID: Rn.43384
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Egln2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001004083.1	NP_001004083.1	3	1222
	XM_006228574.2	XP_006228636.1	3	1232
	XM_006228575.2	XP_006228637.1	3	1271
GenBank mRNA	AY229997.1	-	2	952
	AY952204.1	-	2	952
	BC078907.1	-	3	1222	7113703
	BC081858.1	-	3	1245	7107517

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_080732, NM_053046, AL832506, BC036051, AK074408, and others.
This siRNA also targets the following transcripts in Mouse: NM_053208, BC086764, AK166661, AK152056, AF453879, and others.

Gene Ontology Categories:

Process(es)

response to hypoxia
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
regulation of neuron apoptotic process
cell redox homeostasis
positive regulation of protein catabolic process
oxidation-reduction process

Function(s)

iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxygen sensor activity
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 4-dioxygenase activity