s160505

• Gene Symbol: Arhgef2
• Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 2
• Gene Aliases: -
• Chromosome Location: Chr.2: 187964079 - 188022847 on Build Rnor_6.0
• UniGene ID: Rn.12255
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Arhgef2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001012079.1	NP_001012079.1	6, 7	658
	XM_006232643.2	XP_006232705.1	11, 12	1436
	XM_006232644.2	XP_006232706.1	12, 13	1553
	XM_006232646.2	XP_006232708.1	10, 11	1013
	XM_006232647.2	XP_006232709.1	9, 10	857
	XM_006232648.2	XP_006232710.1	9, 10	808
	XM_006232651.2	XP_006232713.1	6, 7	946
	XM_006232652.2	XP_006232714.1	6, 7	765
	XM_006232653.2	XP_006232715.1	6, 7	653
	XM_006232654.2	XP_006232716.1	6, 7	1462
	XM_008761151.1	XP_008759373.1	12, 13	1548
	XM_008761152.1	XP_008759374.1	7, 8	1536
GenBank mRNA	BC090078.1	-	6, 7	658	7125049
	FQ212011.1	-	7, 8	631

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001198912, NM_001198911, NM_008487, NM_001198913, AF177032, and others.

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
positive regulation of NF-kappaB transcription factor activity
cell division
cellular response to muramyl dipeptide

Function(s)

Rho guanyl-nucleotide exchange factor activity
microtubule binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
metal ion binding
Rac GTPase binding