s161448

• Gene Symbol: Traf2
• Gene Name: Tnf receptor-associated factor 2
• Gene Aliases: -
• Chromosome Location: Chr.3: 2746061 - 2770686 on Build Rnor_6.0
• UniGene ID: Rn.105232
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Traf2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001107815.2	NP_001101285.1	7	859
	XM_006233594.2	XP_006233656.1	8	919
	XM_006233596.2	XP_006233658.1	7	763
	XM_008761588.1	XP_008759810.1	8	865
GenBank mRNA	BC169064.1	-	7	859	5599352

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009422, BC003801, AK159585, AF027570, AK151653, and others.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell cytokine production
protein complex assembly
signal transduction
activation of NF-kappaB-inducing kinase activity
protein catabolic process
positive regulation of interleukin-2 production
tumor necrosis factor-mediated signaling pathway
negative regulation of glial cell apoptotic process
regulation of apoptotic process
positive regulation of JUN kinase activity
cellular protein complex assembly
regulation of JNK cascade
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
protein autoubiquitination
protein homotrimerization
protein K63-linked ubiquitination
cellular response to nitric oxide
positive regulation of protein homodimerization activity
programmed necrotic cell death
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
receptor binding
tumor necrosis factor receptor binding
CD40 receptor binding
protein binding
zinc ion binding
enzyme binding
protein phosphatase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
thioesterase binding
protein complex binding
identical protein binding
sphingolipid binding