s16186 Validated

• Gene Symbol: IKBKG
• Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
• Gene Aliases: AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IKKAP1, IKKG, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
• Chromosome Location: Chr.X: 154542240 - 154565046 on Build GRCh38
• UniGene ID: Hs.43505
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IKBKG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001099856.4	NP_001093326.2	7	1065
	NM_001099857.2	NP_001093327.1	7	1251
	NM_001321396.1	NP_001308325.1	7	1000
	NM_001321397.1	NP_001308326.1	7	1248
	NM_003639.4	NP_003630.1	7	1095
GenBank mRNA	AF062089.1	-	7	947
	AF074382.1	-	7	985
	AF091453.1	-	7	1022
	AF261086.1	-	7	1096
	AY114157.1	-	7	1061
	AY429546.1	-	5	693
	AY429547.1	-	4	577
	AY429548.1	-	2	268
	BC000299.2	-	7	957	2820134
	BC012114.1	-	7	1061	4651870
	BC046922.1	-	7	952	5476394
	BC050612.2	-	7	984	6062527
	BT019621.1	-	6	837
	CA916723.1	-	7	959

More Information

Matching Taqman Gene Expression Assay:

Hs00415849_m1

Gene Ontology Categories:

Process(es)

activation of MAPK activity
stimulatory C-type lectin receptor signaling pathway
transcription, DNA-templated
apoptotic process
inflammatory response
immune response
cellular response to DNA damage stimulus
I-kappaB kinase/NF-kappaB signaling
JNK cascade
response to virus
regulation of tumor necrosis factor-mediated signaling pathway
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
stress-activated MAPK cascade
establishment of vesicle localization
nucleotide-binding oligomerization domain containing signaling pathway
negative regulation of neuron death

Function(s)

signal transducer activity
protein binding
protein domain specific binding
ubiquitin protein ligase binding
protein homodimerization activity
peroxisome proliferator activated receptor binding
metal ion binding
protein heterodimerization activity
K63-linked polyubiquitin binding
linear polyubiquitin binding