s162149

• Gene Symbol: Lck
• Gene Name: LCK proto-oncogene, Src family tyrosine kinase
• Gene Aliases: Lck1, Lcktkr
• Chromosome Location: Chr.5: 147750976 - 147779624 on Build Rnor_6.0
• UniGene ID: Rn.22791
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Lck
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001100709.1	NP_001094179.1	4, 5	386
	XM_006238932.2	XP_006238994.1	5, 6	553
	XM_006238933.2	XP_006238995.1	5, 6	515
	XM_008764140.1	XP_008762362.1	5, 6	571
GenBank mRNA	BC160881.1	-	4, 5	386	7381544

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001162432, NM_001162433, NM_010693, BC011474, X03533, and others.

Gene Ontology Categories:

Process(es)

protein phosphorylation
cellular zinc ion homeostasis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
aging
response to mechanical stimulus
response to metal ion
response to zinc ion
positive regulation of gene expression
dephosphorylation
peptidyl-tyrosine phosphorylation
T cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
response to drug
positive regulation of tyrosine phosphorylation of Stat5 protein
response to hydrogen peroxide
regulation of apoptotic process
innate immune response
positive regulation of gamma-delta T cell differentiation
protein autophosphorylation
B cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of T cell activation
release of sequestered calcium ion into cytosol
positive regulation of uterine smooth muscle contraction
cellular response to peptide hormone stimulus
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

glycoprotein binding
antigen binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein serine/threonine phosphatase activity
receptor binding
ATP binding
protein C-terminus binding
protein kinase binding
protein phosphatase binding
protein complex binding
SH2 domain binding
CD4 receptor binding
CD8 receptor binding
identical protein binding
phosphatidylinositol 3-kinase binding
ATPase binding