s162205

Gene Symbol:

Map3k7 LOC100910771

Gene Name:

mitogen activated protein kinase kinase kinase 7

mitogen-activated protein kinase kinase kinase 7-like

Gene Aliases:

Tak1

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Chromosome Location:

Chr.5: 47185366 - 47244424 on Build Rnor_6.0

Chromosome Location:

Chr.9: 114022059 - 114077887 on Build Rnor_6.0

UniGene ID:

Rn.24019

-

Species:

Rat

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: Map3k7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001107920.2	NP_001101390.2	17	1841
	XM_006237966.2	XP_006238028.1	16	2952

Gene Symbol: LOC100910771
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_003750753.3	XP_003750801.1	17	1817
	XM_006245614.2	XP_006245676.1	16	1736

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003188, NM_145331, NM_145332, NM_145333, AK055901, and others.
This siRNA also targets the following transcripts in Mouse: NM_172688, NM_009316, AK133642, BC006665, AK053911, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
activation of MAPK activity
angiogenesis
neural tube formation
positive regulation of T cell cytokine production
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
transforming growth factor beta receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
I-kappaB phosphorylation
JNK cascade
positive regulation of interleukin-2 production
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
histone H3 acetylation
positive regulation of JNK cascade
stress-activated MAPK cascade
negative regulation of necroptotic process
negative regulation of ripoptosome assembly involved in necroptotic process
regulation of reactive oxygen species metabolic process
negative regulation of reactive oxygen species metabolic process
negative regulation of apoptotic signaling pathway

Function(s)

magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
scaffold protein binding