s1658

• Gene Symbol: ASCL1
• Gene Name: achaete-scute family bHLH transcription factor 1
• Gene Aliases: ASH1, HASH1, MASH1, bHLHa46
• Chromosome Location: Chr.12: 102957674 - 102960516 on Build GRCh38
• UniGene ID: Hs.703025
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ASCL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004316.3	NP_004307.2	2	2235
GenBank mRNA	BC001638.2	-	2	2222
	BC004425.1	-	2	2222	2819879

More Information

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
noradrenergic neuron development
noradrenergic neuron fate commitment
transcription, DNA-templated
Notch signaling pathway
regulation of mitotic cell cycle
neuroblast fate determination
neuroblast proliferation
response to lithium ion
regulation of gene expression
oligodendrocyte development
spinal cord association neuron differentiation
spinal cord oligodendrocyte cell fate specification
vestibular nucleus development
cerebral cortex GABAergic interneuron differentiation
commitment of neuronal cell to specific neuron type in forebrain
central nervous system neuron development
cerebral cortex development
neurogenesis
regulation of epithelial cell differentiation
response to retinoic acid
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
sympathetic nervous system development
neuron fate specification
musculoskeletal movement, spinal reflex action
response to folic acid
subpallium neuron fate commitment
regulation of timing of subpallium neuron differentiation
olfactory pit development
lung epithelial cell differentiation
ventral spinal cord interneuron fate commitment
lung neuroendocrine cell differentiation
stomach neuroendocrine cell differentiation
carotid body glomus cell differentiation
adrenal chromaffin cell differentiation
sympathetic ganglion development
response to epidermal growth factor
cellular response to magnetism
positive regulation of neural precursor cell proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein homodimerization activity
bHLH transcription factor binding
E-box binding