s166530

• Gene Symbol: Pf4
• Gene Name: platelet factor 4
• Gene Aliases: Cxcl4, PF-4, Pf4a, RATPF4A
• Chromosome Location: Chr.14: 18848549 - 18849258 on Build Rnor_6.0
• UniGene ID: Rn.6800
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pf4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001007729.1	NP_001007730.1	2	166

More Information

Panther Classification:

Molecular Function -

chemokine

Gene Ontology Categories:

Process(es)

positive regulation of leukocyte chemotaxis
protein complex assembly
inflammatory response
immune response
G-protein coupled receptor signaling pathway
positive regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
negative regulation of angiogenesis
cytokine-mediated signaling pathway
platelet activation
leukocyte chemotaxis
positive regulation of cAMP metabolic process
response to lipopolysaccharide
positive regulation of tumor necrosis factor production
regulation of cell proliferation
positive regulation of cAMP-mediated signaling
negative regulation of MHC class II biosynthetic process
positive regulation of macrophage differentiation
negative regulation of megakaryocyte differentiation
negative regulation of cytolysis
positive regulation of transcription from RNA polymerase II promoter
chemokine-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

molecular_function
chemokine activity
heparin binding
CXCR chemokine receptor binding
CXCR3 chemokine receptor binding