s16756 Validated

• Gene Symbol: TNFRSF10B
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Chromosome Location: Chr.8: 23020133 - 23069187 on Build GRCh38
• UniGene ID: Hs.521456
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFRSF10B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003842.4	NP_003833.4	9	1457
	NM_147187.2	NP_671716.2	10	1370
	NR_027140.1		9	1264
	XM_017013944.1	XP_016869433.1	9	1245
GenBank mRNA	AB451272.1	-	9	1164
	AB451399.1	-	9	1164
	AF012535.1	-	10	1216
	AF012628.1	-	10	1077
	AF016266.1	-	9	1281
	AF016268.1	-	10	1186
	AF016849.1	-	9	1308
	AF018657.1	-	10	1077
	AF018658.1	-	9	1164
	AF020501.1	-	10	1077
	AF022386.1	-	10	1077
	AF153687.1	-	10	1195
	AF192548.1	-	10	1177
	AK291216.1	-	9	1284
	AK296128.1	-	5	470
	AK298602.1	-	9	1108
	AY358277.1	-	10	1216
	BC001281.1	-	9	1311	3458466
	BX537617.1	-	4	562
	BX538104.1	-	9	1286
	BX538179.1	-	4	562
	CR541898.1	-	9	1164
	CX870630.1	-	5	669
	FJ200482.1	-	8	1058

More Information

Matching Taqman Gene Expression Assay:

Hs00366272_m1

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding