s169222

• Gene Symbol: Topors
• Gene Name: topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
• Gene Aliases: -
• Chromosome Location: Chr.5: 56554956 - 56566503 on Build Rnor_6.0
• UniGene ID: Rn.55605
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Topors
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001108658.1	NP_001102128.1	3	2217

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
protein monoubiquitination
cellular response to DNA damage stimulus
intrinsic apoptotic signaling pathway in response to DNA damage
protein sumoylation
protein localization to nucleus
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of transcription, DNA-templated
positive regulation of ubiquitin-protein transferase activity
maintenance of protein location in nucleus
protein K48-linked ubiquitination

Function(s)

DNA binding
antigen binding
ubiquitin-protein transferase activity
zinc ion binding
isomerase activity
SUMO transferase activity
DNA topoisomerase binding
ubiquitin protein ligase activity