s169558

• Gene Symbol: Tp73
• Gene Name: tumor protein p73
• Gene Aliases: P73, Trp73
• Chromosome Location: Chr.5: 171355876 - 171415354 on Build Rnor_6.0
• UniGene ID: Rn.103860
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tp73
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001108696.1	NP_001102166.1	5	593

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011642, NM_001126331, NM_001126330, Y19234, BC066045, and others.

Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
kidney development
release of cytochrome c from mitochondria
transcription from RNA polymerase II promoter
inflammatory response
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
cell cycle arrest
regulation of mitotic cell cycle
post-embryonic development
response to X-ray
response to organonitrogen compound
response to gamma radiation
regulation of gene expression
hippocampus development
forebrain development
mitotic G1 DNA damage checkpoint
cerebrospinal fluid secretion
cellular response to UV
response to drug
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
negative regulation of JUN kinase activity
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of cell size
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
digestive tract morphogenesis
neuron development
positive regulation of oligodendrocyte differentiation
protein tetramerization
negative regulation of cardiac muscle cell proliferation
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein kinase binding
identical protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding