s169851

• Gene Symbol: Dot1l
• Gene Name: DOT1-like histone H3K79 methyltransferase
• Gene Aliases: -
• Chromosome Location: Chr.7: 11786105 - 11824742 on Build Rnor_6.0
• UniGene ID: Rn.228827
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dot1l
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001108733.1	NP_001102203.1	11, 12	1233
	XM_006240959.2	XP_006241021.1	11, 12	1185
	XM_006240960.2	XP_006241022.1	11, 12	1185
	XM_006240961.2	XP_006241023.1	11, 12	1039

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_032482, AK074120, AF509504.
This siRNA also targets the following transcripts in Mouse: NM_199322, AY377920, AY196089, AK035144, JF508521, and others.

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein, histone modifying enzyme

Gene Ontology Categories:

Process(es)

chromatin silencing
biological_process
histone methylation
histone H3-K79 methylation
regulation of JAK-STAT cascade
regulation of cell cycle
regulation of transcription regulatory region DNA binding

Function(s)

molecular_function
DNA binding
transcription factor binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K79 specific)
histone methyltransferase activity