s170581

• Gene Symbol: Als2
• Gene Name: amyotrophic lateral sclerosis 2 (juvenile)
• Gene Aliases: -
• Chromosome Location: Chr.9: 65961361 - 66034402 on Build Rnor_6.0
• UniGene ID: Rn.219733
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Als2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001013413.1	NP_001013431.1	22	3685
	XM_006245001.2	XP_006245063.1	23	4020
GenBank mRNA	AB190511.1	-	1	68

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_028717, NM_001159948, AK014320, AB053307, CN715620, and others.

Gene Ontology Categories:

Process(es)

behavioral fear response
in utero embryonic development
receptor recycling
response to oxidative stress
endosome organization
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
synaptic transmission, glutamatergic
positive regulation of protein kinase activity
neuron projection morphogenesis
regulation of endosome size
positive regulation of protein serine/threonine kinase activity

Function(s)

molecular_function
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity