s170679

• Gene Symbol: Hdac4
• Gene Name: histone deacetylase 4
• Gene Aliases: -
• Chromosome Location: Chr.9: 99052945 - 99299715 on Build Rnor_6.0
• UniGene ID: Rn.23483
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053449.1	NP_445901.1	14	2099
	XM_006245438.1	XP_006245500.1	14	2326
	XM_006245440.1	XP_006245502.1	14	2311
	XM_006245441.1	XP_006245503.1	14	2326
	XM_006245442.1	XP_006245504.1	14	2311
	XM_006245443.1	XP_006245505.1	14	2103
	XM_008767278.1	XP_008765500.1	13	2095
	XM_008767279.1	XP_008765501.1	13	7986

More Information

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
osteoblast development
chromatin remodeling
transcription, DNA-templated
protein deacetylation
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of lamellipodium assembly
negative regulation of myotube differentiation
regulation of cardiac muscle contraction by calcium ion signaling
response to denervation involved in regulation of muscle adaptation
positive regulation of smooth muscle cell migration
histone deacetylation
positive regulation of protein sumoylation
peptidyl-lysine deacetylation
regulation of gene expression, epigenetic
response to drug
regulation of protein binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
negative regulation of osteoblast differentiation
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
regulation of skeletal muscle fiber development
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of striated muscle cell differentiation
histone H3-K9 modification
response to interleukin-1
histone H3 deacetylation
histone H4 deacetylation
cellular response to mechanical stimulus
cellular response to tumor necrosis factor
cellular response to parathyroid hormone stimulus
positive regulation of reactive oxygen species biosynthetic process

Function(s)

RNA polymerase III transcription factor binding
core promoter binding
molecular_function
DNA binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
zinc ion binding
protein kinase binding
potassium ion binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
activating transcription factor binding
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
repressing transcription factor binding
NAD-dependent histone deacetylase activity (H3-K18 specific)