s1720 Validated

• Gene Symbol: ATP1A1
• Gene Name: ATPase Na+/K+ transporting subunit alpha 1
• Gene Aliases: -
• Chromosome Location: Chr.1: 116373173 - 116404774 on Build GRCh38
• UniGene ID: Hs.371889
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATP1A1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000701.7	NP_000692.2	4	695
	NM_001160233.1	NP_001153705.1	4	719
	NM_001160234.1	NP_001153706.1	4	528
	XM_017001360.1	XP_016856849.1	5	3914
	XM_017001361.1	XP_016856850.1	5	3256
GenBank mRNA	AK293689.1	-	1	100
	AK295095.1	-	4	718
	AK296362.1	-	4	528
	AK296384.1	-	4	654
	AK308418.1	-	4	460
	AK314777.1	-	4	540
	AL531892.3	-	4	662
	BC003077.2	-	4	608	3507685
	BC050359.1	-	4	606	6065209
	U16798.1	-	3	356

More Information

Matching Taqman Gene Expression Assay:

Hs00167556_m1

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

regulation of the force of heart contraction
regulation of sodium ion transport
cellular sodium ion homeostasis
regulation of blood pressure
potassium ion import
establishment or maintenance of transmembrane electrochemical gradient
ATP hydrolysis coupled proton transport
dephosphorylation
cellular potassium ion homeostasis
negative regulation of glucocorticoid biosynthetic process
ion transmembrane transport
sodium ion export from cell
response to drug
negative regulation of heart contraction
positive regulation of heart contraction
positive regulation of striated muscle contraction
relaxation of cardiac muscle
cardiac muscle contraction
membrane hyperpolarization
cellular response to mechanical stimulus
cellular response to steroid hormone stimulus
regulation of cardiac muscle cell contraction
membrane repolarization
membrane repolarization during cardiac muscle cell action potential
cell communication by electrical coupling involved in cardiac conduction
response to glycoside
regulation of cardiac conduction
potassium ion import across plasma membrane

Function(s)

sodium:potassium-exchanging ATPase activity
protein binding
ATP binding
phosphatase activity
protein kinase binding
protein domain specific binding
ankyrin binding
potassium ion binding
sodium ion binding
ADP binding
phosphatidylinositol 3-kinase binding
chaperone binding
steroid hormone binding