s1759 Validated

• Gene Symbol: ATP2B4
• Gene Name: ATPase plasma membrane Ca2+ transporting 4
• Gene Aliases: ATP2B2, MXRA1, PMCA4, PMCA4b, PMCA4x
• Chromosome Location: Chr.1: 203626787 - 203744081 on Build GRCh38
• UniGene ID: Hs.343522
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATP2B4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001001396.2	NP_001001396.1	12	2812
	NM_001684.4	NP_001675.3	12	2812
GenBank mRNA	AK292458.1	-	11	2151
	BC140774.1	-	12	2484	9021642
	BC150293.1	-	11	2169	8860318
	BX537444.1	-	12	3039
	CR749393.1	-	12	2742
	CR936708.1	-	12	2767
	M25874.1	-	11	2312
	M83363.1	-	11	2312

More Information

Matching Taqman Gene Expression Assay:

Hs00608066_m1

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

neural retina development
regulation of transcription from RNA polymerase II promoter
cellular calcium ion homeostasis
spermatogenesis
negative regulation of nitric oxide mediated signal transduction
hippocampus development
sperm motility
positive regulation of peptidyl-serine phosphorylation
ion transmembrane transport
negative regulation of nitric oxide biosynthetic process
negative regulation of nitric-oxide synthase activity
response to hydrostatic pressure
calcium ion transmembrane transport
negative regulation of calcineurin-NFAT signaling cascade
cellular response to epinephrine stimulus
calcium ion transmembrane import into cytosol
calcium ion import across plasma membrane
negative regulation of the force of heart contraction
negative regulation of arginine catabolic process
negative regulation of adrenergic receptor signaling pathway involved in heart process
calcium ion export
negative regulation of peptidyl-cysteine S-nitrosylation
regulation of sodium ion transmembrane transport
regulation of cell cycle G1/S phase transition
negative regulation of cardiac muscle hypertrophy in response to stress
negative regulation of citrulline biosynthetic process
regulation of cardiac conduction
positive regulation of cAMP-dependent protein kinase activity

Function(s)

calcium-transporting ATPase activity
protein binding
calmodulin binding
ATP binding
sodium channel regulator activity
PDZ domain binding
protein phosphatase 2B binding
nitric-oxide synthase inhibitor activity
metal ion binding
nitric-oxide synthase binding
scaffold protein binding