s176366

• Gene Symbol: Ern1
• Gene Name: endoplasmic reticulum to nucleus signaling 1
• Gene Aliases: RGD1559716
• Chromosome Location: Chr.10: 94588555 - 94681985 on Build Rnor_6.0
• UniGene ID: Rn.226435
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ern1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001191926.1	NP_001178855.1	19, 20	2501
	XM_006247633.2	XP_006247695.1	19, 20	2752
	XM_006247634.2	XP_006247696.1	19, 20	2745

More Information

Panther Classification:

Molecular Function -

endoribonuclease

Gene Ontology Categories:

Process(es)

endothelial cell proliferation
mRNA cleavage
protein phosphorylation
activation of signaling protein activity involved in unfolded protein response
cell cycle arrest
RNA splicing
endoplasmic reticulum unfolded protein response
mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response
positive regulation of RNA splicing
cellular response to vascular endothelial growth factor stimulus
protein autophosphorylation
mRNA splicing, via endonucleolytic cleavage and ligation
mRNA endonucleolytic cleavage involved in unfolded protein response
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of endoplasmic reticulum unfolded protein response
peptidyl-serine trans-autophosphorylation

Function(s)

magnesium ion binding
endonuclease activity
endoribonuclease activity
protein serine/threonine kinase activity
ATP binding
enzyme binding
identical protein binding
protein homodimerization activity
ADP binding